The wrinkles that appear on the face are caused by three basic reasons: by the imprint of the facial expression , by the loss of volume of the skin tissue associated with the passage of time and by the accumulated damage of ultraviolet radiation . In addition to these three major factors, there are other associated conditions that can accentuate their appearance, such as tobacco, the genetic load or the hormonal status of the person.
The expressive component of facial wrinkles is very effectively blurred by the use of botulinum toxin. However, the fixed and volume-losing component of wrinkles does not respond to this therapy and can be treated with hyaluronic acid fillers. This is a molecule naturally present in the skin, with the mission of providing elasticity and volume to the tissue. Hyaluronic acid has a high hygroscopic potential: it absorbs a large amount of the water present in the skin environment and increases its volume and turgor. Over time, the hyaluronic acid that we have in the dermis is lost and there is a contraction of the dermis, reflected externally with the appearance of wrinkles and the loss of the contour of the face.
To reduce its progressive loss, it is possible to provide hyaluronic acid externally through gentle microinjections into the dermis. This contribution allows the skin to be hydrated, lost volume to be replenished and wrinkles to be eliminated in a simple and discreet way. The effects of this procedure are practically immediate, and allow superficial and deep wrinkles to be smoothed or eliminated. It is also used to restore lost volume around the lips, cheekbones or chin, or to remove depressed scars .
→ Hyaluronic acid fillers are approved by the FDA (Food and Drug Administration, USA) for aesthetic treatment due to their safety and quality. Click here for more details.

Click here to find out the main characteristics of hyaluronic acid.
Bibliographic references
Sturm LP, Cooter RD, Mutimer KL, Graham JC, Maddern GJ. A systematic review of dermal fillers for age-related lines and wrinkles. ANZ J Surg. 2011 Jan; 81(1-2):9-17.
Bray D, Hopkins C, Roberts DN. A review of dermal fillers in facial plastic surgery. Curr Opin Otolaryngol Head Neck Surg. 2010 Aug; 18(4):295-302.